Endocrine Abstracts

Introduction: In post-menopausal women, the differential diagnosis of hirsutism caused by testosterone excess includes ovarian and adrenal sources. Bilateral ovarian hyperthecosis is a common cause of testosterone excess in post-menopausal women and the diagnosis is confirmed by histopathological examination of the ovaries. Adrenal tumors causing testosterone excess is exceedingly rare. In fact, most causes of hirsutism secondary to adrenal tumors is due to dehydroepiandroster...

Background: Chronic opioid use may lead to adrenal insufficiency (AI) due to suppression of the hypothalamic-pituitary-adrenal axis. We aimed to determine incidence of AI and mortality in patients treated with chronic opioid therapy in a standardized geographically well-defined population.Methods: In this population-based cohort study we assessed the standardized incidence rate of first time met chronic opioid use and adrenal insufficiency in adult resid...